osteoporosis is syndrome

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Osteoporosis is a real illness or an unavoidable condition, age-related?
More than a “disease” osteoporosis is a “syndrome” that is a disease affected by many factors and contributing factors not completely understood.
To better understand the mechanisms through which the bone can become Porot, tenuous and fragile until losing the characteristics of its own resilience and strength, it is important to know the fundamental moments that regulate normal growth and metabolism.
Contrary to what may be considered, the bone is not an inert structure, but a very active tissue from the metabolic point of view, which is renewed continuously and rapidly throughout life. The general structure of the skeleton is represented by a substrate of protein very resistant and elastic (collagen) in the context of which are deposited crystals of calcium phosphate (hydroxyapatite), which give rigidity and consistency.
Individual adult skeleton contains almost 99% of all the calcium in the body.
The provision of calcified tissue that is characteristic: in the outer bone (cortical) is particularly dense in (trabecular component) takes on a beehive that helps make it lighter without reducing the load bearing capacity.
The compact cortical bone is almost 80% of the total and is mainly represented in the long bones (arms and legs), trabecular bone is approximately 20% of the total and is especially present in the inner part of the vertebral bodies.
The bone also has a cellular component, like any other tissue.
Its cells are highly specialized and dedicated to the formation of new bone (osteoblasts), destruction and bone resorption in aged (osteoclasts), and probably the independent regulation of these two activities (osteocytes).
The general metabolic process is called “remodeling.”
Under normal circumstances it takes place in a predetermined sequence: the first involved the osteoclasts, which produce a small resorption cavity, this cavity is then filled by new bone calcified by osteoblasts, and so on, with continuous cycles of total duration each 90 days. If the amount of newly formed bone is equal to that absorbed by bone is a metabolic equilibrium.
Osteoporosis occurs as a final event in a series of cycles over which is resorbed more bone than it forms.
This may be because the osteoclasts work too much or too little work because the osteoblasts, or both causes combined.
Since the remodeling as a whole is governed by an enormous number of factors (hormones, drugs, physical activity, local diseases etc..) Cases which may lead to imbalance of the processes of formation and resorption, and osteoporosis are so very many .

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